TOXICITY ASSESSMENT OF NANOFIBER PREPARED WITHTARRAGON

Abstract: Nanofiber materials are not only used in many areas but also impregnate various plant extracts, thus providing advantages for the pharmaceutical, medical and biomedical sectors. In our study, we evaluated the toxic effect of Tarragon (Artemesia dracunculus, 600 - 2000 μg / L) and the nanofiber (260 nm) prepared by electrospinning method on 3rd instar larvae of Drosophila melanogaster. Controlled experiments were carried out in the laboratory between 24-120 hours. Statistical analyzes were performed among the groups, including positive and negative controls. It has been observed that the application of nanofiber with Tarragon reduces mortality at all concentrations compared to only tarragon application and increases the formation of pupa and adult individual in the same direction.